Gene information
Official symbol NFATC1
Official full name nuclear factor of activated T cells 1
Gene type protein-coding gene
Chromosome18q23
Alias symbolNF-ATC; NFATc; NFAT2
Gene familyNuclear factors of activated T-cells ; IPT domain containing
Resources
Entrez Gene 4772
HGNC HGNC:7775
Ensembl ENSG00000131196
Vega OTTHUMG00000132897
UCSC uc002lnd.4
GO terms: 25 records
GO Description Category LogP Number of genes Detail
GO:0001216 DNA-binding transcription activator activity GO Molecular Functions -9.83829980 29 More
GO:0001221 transcription coregulator binding GO Molecular Functions -4.88806294 16 More
GO:0001223 transcription coactivator binding GO Molecular Functions -2.21174835 6 More
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific GO Molecular Functions -9.92639238 29 More
GO:0003170 heart valve development GO Biological Processes -11.9253160 20 More
GO:0003176 aortic valve development GO Biological Processes -8.77845673 13 More
GO:0003177 pulmonary valve development GO Biological Processes -7.13135320 9 More
GO:0003179 heart valve morphogenesis GO Biological Processes -9.26383069 16 More
GO:0003180 aortic valve morphogenesis GO Biological Processes -6.3383802 10 More
GO:0003184 pulmonary valve morphogenesis GO Biological Processes -5.51502780 7 More
GO:0005667 transcription regulator complex GO Cellular Components -7.37095162 26 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0008134 transcription factor binding GO Molecular Functions -5.50998540 50 More
GO:0019722 calcium-mediated signaling GO Biological Processes -11.6647584 29 More
GO:0019900 kinase binding GO Molecular Functions -6.03057706 62 More
GO:0019901 protein kinase binding GO Molecular Functions -6.66055444 59 More
GO:0019932 second-messenger-mediated signaling GO Biological Processes -19.1717114 46 More
GO:0030111 regulation of Wnt signaling pathway GO Biological Processes -7.94227486 39 More
GO:0030178 negative regulation of Wnt signaling pathway GO Biological Processes -7.69726068 26 More
GO:0033218 amide binding GO Molecular Functions -9.50305686 47 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0051148 negative regulation of muscle cell differentiation GO Biological Processes -3.93077688 11 More
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding GO Molecular Functions -8.00802452 40 More
GO:0140297 DNA-binding transcription factor binding GO Molecular Functions -6.94737226 46 More
GO:1905314 semi-lunar valve development GO Biological Processes -10.3278393 15 More
KEGG pathways: 4 records
KEGG Description Category LogP Number of genes Detail
hsa04024 cAMP signaling pathway KEGG Pathway -7.78464854 30 More
hsa04310 Wnt signaling pathway KEGG Pathway -2.72762629 16 More
hsa04380 Osteoclast differentiation KEGG Pathway -7.05199617 21 More
hsa04658 Th1 and Th2 cell differentiation KEGG Pathway -5.18694144 15 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
Chr18:79403051 hypomethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
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